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. 2022 Dec 12;10:974851. doi: 10.3389/fcell.2022.974851

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Copyright © 2022 Zhang, Lyu, Andreev, Jia, Zhang and Bozec.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of immune status and immune-associated DEGs in osteosarcoma. (A) Enrichment levels of 29 immune signatures in the immune-high and immune-low groups in the TARGET dataset. (B) K-M plot of overall survival for patients in immune-high and immune-low groups in the TARGET dataset. (C) Comparison of 22 infiltrating immune cells between immune-low and immune-high groups in the TARGET dataset. (D) Volcano plot showing the DEGs between immune-high and immune-low groups in the TARGET dataset. (E) GO analysis of DEGs between immune-high and immune-low groups in the TARGET dataset. Asterisks mark statistically significant difference. *p < 0.05, **p < 0.01, ***p < 0.001.