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. 2022 Dec 12;13:1001778. doi: 10.3389/fmicb.2022.1001778

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Copyright © 2022 Jiang, Mao, Sun, Shi, Han, Zhang, Zhang, Wang, Hu, Zhang, Li and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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YLZD remodeled the composition of gut microbiota. (A,B) The bacterial diversity in intestinal estimated by alpha-diversity of chao and Shannon indexes. (C) Venn diagram of the overlap of the OTUs in the gut microbiota in different treatments. (D) The β-diversity analysis of Principal Coordinate Analysis (PCoA). (E) Bar plot of the gut microbiota at the phylum level. (F) Bar plot of the gut microbiota at the genus level. (G) The ratio of Firmicutes to Bacteroidetes. (H–M) Changes in the abundance of Christensenellaceae, Clostridia_UCG-014, Muribaculaceae, Prevotellaceae, Oribacterium and Lactobacillus, respectively. Values are represented as mean ± SEM (n = 6 rats/group). ^##p < 0.01, ^#p < 0.05 versus the Control group; ^**p < 0.01, ^*p < 0.05 versus the HFD group.