Table 1.
Renal changes during acute renal ischemia and recovery by multi-parametric MRI
| Baseline | 50% RAS | 75% RAS | 100% RAS | Recovery | |
|---|---|---|---|---|---|
| Perfusion (mL/mL/min) | |||||
| Cortex | 2.19±0.63 | 0.67±0.47* | 0.45±0.19* | 0.38±0.13* | 0.83±0.43*& |
| Medulla | 1.26±0.32 | 0.34±0.35* | 0.21±0.05* | 0.17±0.03* | 0.74±0.39*#$& |
| R2* (s−1) | |||||
| Cortex | 17.8±1.8 | 31.2±9.4* | 50.6±13.6*# | 57.1±18.1*# | 19.5±6.9#$& |
| Medulla | 20.2±2.5 | 41.8±13.4* | 64.1±13.3*# | 67.2±13.5*# | 19.1±3.7#$& |
| Stiffness (kPa) | |||||
| Cortex | 4.76±0.49 | 3.72±0.34* | 3.79±0.47* | 3.66±0.57* | 6.19±1.46#$& |
| Medulla | 4.54±0.53 | 3.59±0.20* | 3.46±0.39* | 3.40±0.42* | 5.31±0.97#$& |
| ADC (×10−3mm2/s) | |||||
| Cortex | 1.54±0.21 | 0.94±0.22* | 0.87±0.18* | 0.82±0.19* | 1.41±0.07#$& |
| Medulla | 1.51±0.23 | 0.99±0.19* | 0.94±0.16* | 0.95±0.15* | 1.51±0.16#$& |
| MTR at 600 Hz | |||||
| Cortex | 0.81±0.03 | 0.81±0.05 | 0.80±0.04 | 0.79±0.04 | 0.77±0.03*# |
| Medulla | 0.75±0.04 | 0.76±0.05 | 0.77±0.04 | 0.75±0.03 | 0.73±0.05 |
| MTR at 1000 Hz | |||||
| Cortex | 0.76±0.03 | 0.78±0.06 | 0.76±0.04 | 0.74±0.04 | 0.64±0.05*# |
| Medulla | 0.67±0.03 | 0.71±0.05 | 0.71±0.02 | 0.69±0.04 | 0.73±0.05 |
Data are means ± standard deviations. MRI=magnetic resonance imaging; RAS=renal artery stenosis; ADC=apparent diffusion coefficient; MTR=magnetization transfer ratio.
P<0.05 vs. Baseline
P<0.05 vs. 50% RAS
P<0.05 vs. 75% RAS
P<0.05 vs. 100% RAS.