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. 2022 Dec 12;10:1066504. doi: 10.3389/fcell.2022.1066504

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Copyright © 2022 Khakurel, Kudlyk, Pokrovskaya, D’Souza and Lupashin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GARP dysfunction alters Golgi homeostasis and Golgi trafficking machineries. A cartoon depicting Golgi trafficking machinery in WT and GARP-KO cells. Proper maintenance of Golgi structure, calcium channel and Golgi trafficking machinery including SNAREs, COPI coats, ARFGEFs in control cells (Left panel). Disruption of the Golgi structure, calcium channel, and Golgi trafficking machineries in GARP-KO cells (right panel).