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. 2022 Dec 12;13:1092370. doi: 10.3389/fimmu.2022.1092370

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Copyright © 2022 Bishop, Caten, Nakaya and Suhrbier

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pearson correlations for IPA USRs with other infections and rheumatoid arthritis. The DEGs from whole blood of CHIKV-infected Adults were analyzed by IPA to provide z-scores for significant USRs and USRs for (Molecule type) Cytokine, Biologic drug and Chemical drug. These z-scores were compared by Pearson correlations with z-scores from peripheral blood mononuclear cells (PBMC) from children with bronchiolitis and Adults infected with SARS-CoV-2, as well as synovial biopsies from rheumatoid arthritis (RA) patients. Coefficients of determination (r²) are plotted.