Table 1.
Origins of human and mouse gene expression datasets.
| Groups | NCBI BioProject | Infectedtissue | Control tissue | Library prep. | RNA-SeqPlatform | Notes |
|---|---|---|---|---|---|---|
| Mice Ft 2 dpi Ft 7 dpi LN 2 dpi LN 7dpi |
PRJNA431476 | Hind Ft Inguinal LN |
Hind Ft Inguinal LN from mock infected mice |
Poly-A selected | Illumina HiSeq 2000 | 2 dpi peak viremia 7 dpi peak arthritis |
| Human Children |
PRJNA390289 | Whole peripheral blood acute phase | Whole peripheral blood convalescent phase | Total RNA, ribo/globin RNA depleted | Illumina HiSeq 4000 | Technical replicates collapsed |
| Human Adults |
PRJNA507472 | Whole peripheral blood acute phase | Whole peripheral blood healthy subjects | Total RNA, ribo/globin RNA depleted | Illumina HiSeq 1500 |
The source and treatment of the RNA-Seq data sets from mouse and human studies. All fastq files were reanalyzed using STAR, RSEM and EdgeR to provide consistency across groups. Ft – feet, LN – lymph nodes, dpi days post infection.