Table 2.
Body weight, rectal temperature, and packed cell volume of P. berghei-infected mice treated with hydroalcoholic leaves extract of C. latifolia in the 4-day suppressive test.
Group | Weight |
Rectal Temperature |
Packed cell volume |
||||||
---|---|---|---|---|---|---|---|---|---|
D0 | D4 | % Change | D0 | D4 | % Change | D0 | D4 | % Change | |
DW | 27.16 ± 0.32 | 22.66 ± 0.21 | −16.55 ± 0.57 | 37.10 ± 0.99 | 31.34 ± 0.10 | −15.52 ± 0.14 | 55.73 ± 0.76 | 46.64 ± 0.66 | −16.31 ± 0.41 |
CQ 25 | 26.54 ± 0.57 | 26.65 ± 0.60 | .39 ± 0.15 | 36.90 ± 0.11 | 36.78 ± 0.11 | −.31 ± 0.10 | 55.98 ± 0.64 | 55.63 ± 0.62 | −.62 ± 0.17 |
CLCE100 | 25.95 ± 0.56 | 23.04 ± 0.53 | −11.21 ± 0.75a3b3d2e3 | 37.04 ± 0.06 | 32.32 ± 0.14 | −12.74 ± 0.30a3b3d2e3 | 55.0 ± 600 | 48.36 ± 0.44 | −12.16 ± 0.39a3b3d2e3 |
CLCE200 | 25.24 ± 0.74 | 23.42 ± 0.66 | −7.1998 ± 0.35a3b3e3 | 36.8 ± 0.07 | 33.62 ± 0.07 | −8.64 ± 0.09a3b3e3 | 55.44 ± 0.49 | 50.7 ± 0.34 | −8.53 ± 0.39a3b3e3 |
CLCE400 | 26.10 ± 0.67 | 25.16 ± 0.71 | −3.62 ± 0.53a3b3 | 37.00 ± 0.10 | 35.38 ± 0.11 | −4.39 ± 0.10a3b3 | 53.73 ± 0.72 | 51.10 ± 0.78 | −4.91 ± 0.34a3b3 |
Data are expressed as mean ± SEM; n = 5; compared to a, negative control; b, CQ25 mg/kg; c, 100 mg/kg; d, 200 mg/kg; e, 400 mg/kg; 1, P < 0.05; 2, P < 0.01; 3, P < 0.001; DW, distilled water; CQ, chloroquine; CLCE, crude extract of the Commelina latifolia; D0, pre-treatment value on day 0; D4, post-treatment value on day 4.