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. 2022 Dec 10;8(12):e12045. doi: 10.1016/j.heliyon.2022.e12045

Table 3.

Body weight, rectal temperature, and packed cell volume of P. berghei-infected mice treated with hydroalcoholic leaves extract of C. latifolia in the Rane's test.

Group Bodyweight
Rectal temperature
Packed cell volume
D3 D7 %change D3 D7 %change D3 D7 %change
DW 26.29 ± 0.50 22.56 ± 0.50 −14.20 ± 0.64 36.88 ± 0.15 32.10 ± 0.24 −12.96 ± 0.45 55.55 ± 0.52 48.40 ± 0.68 −12.88 ± 0.56
CQ 25.88 ± 0.25 26.26 ± 0.24 1.47 ± 0.15a3 36.83 ± 0.12 36.66 ± 0.09 −0.47 ± 0.12a3 54.73 ± 0.67 54.37 ± 0.61 −0.66 ± 0.29a3
CL100 26.81 ± 0.17 24.47 ± 0.20 −8.73 ± 0.49a3b3e3 36.74 ± 0.12 33.12 ± 0.15 −9.8524 ± 0.31a3b3d3e3 54.60 ± 0.64 49.20 ± 0.49 −9.88 ± 0.23a3b3d3e3
CL200 25.60 ± 0.50 23.94 ± 0.46 −6.47 ± 0.66a3b3e1 36.42 ± 0.14 33.80 ± 0.16 −7.19 ± 0.15a3b3e3 55.56 ± 0.91 51.70 ± 0.98 −6.96 ± 0.45a3b3
CL400 24.98 ± 0.45 24.10 ± 0.55 −3.55 ± 0.77a3b3 36.68 ± 0.22 35.24 ± 0.27 −3.93 ± 0.29a3b3 55.32 ± 0.89 52.40 ± 0.77 −5.30 ± 0.48a3b3

Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 25 mg/kg; d, to 50 mg/kg; e, to 100 mg/kg; 1, P < 0.05; 2, P < 0.01; 3, P < 0.001; DW, distilled water; CQ, chloroquine; CL, crude extract of Commelina latifolia; D3, pre-treatment value on day 3; D7, post-treatment value on day 7.