Table 3.
Body weight, rectal temperature, and packed cell volume of P. berghei-infected mice treated with hydroalcoholic leaves extract of C. latifolia in the Rane's test.
| Group | Bodyweight |
Rectal temperature |
Packed cell volume |
||||||
|---|---|---|---|---|---|---|---|---|---|
| D3 | D7 | %change | D3 | D7 | %change | D3 | D7 | %change | |
| DW | 26.29 ± 0.50 | 22.56 ± 0.50 | −14.20 ± 0.64 | 36.88 ± 0.15 | 32.10 ± 0.24 | −12.96 ± 0.45 | 55.55 ± 0.52 | 48.40 ± 0.68 | −12.88 ± 0.56 |
| CQ | 25.88 ± 0.25 | 26.26 ± 0.24 | 1.47 ± 0.15a3 | 36.83 ± 0.12 | 36.66 ± 0.09 | −0.47 ± 0.12a3 | 54.73 ± 0.67 | 54.37 ± 0.61 | −0.66 ± 0.29a3 |
| CL100 | 26.81 ± 0.17 | 24.47 ± 0.20 | −8.73 ± 0.49a3b3e3 | 36.74 ± 0.12 | 33.12 ± 0.15 | −9.8524 ± 0.31a3b3d3e3 | 54.60 ± 0.64 | 49.20 ± 0.49 | −9.88 ± 0.23a3b3d3e3 |
| CL200 | 25.60 ± 0.50 | 23.94 ± 0.46 | −6.47 ± 0.66a3b3e1 | 36.42 ± 0.14 | 33.80 ± 0.16 | −7.19 ± 0.15a3b3e3 | 55.56 ± 0.91 | 51.70 ± 0.98 | −6.96 ± 0.45a3b3 |
| CL400 | 24.98 ± 0.45 | 24.10 ± 0.55 | −3.55 ± 0.77a3b3 | 36.68 ± 0.22 | 35.24 ± 0.27 | −3.93 ± 0.29a3b3 | 55.32 ± 0.89 | 52.40 ± 0.77 | −5.30 ± 0.48a3b3 |
Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 25 mg/kg; d, to 50 mg/kg; e, to 100 mg/kg; 1, P < 0.05; 2, P < 0.01; 3, P < 0.001; DW, distilled water; CQ, chloroquine; CL, crude extract of Commelina latifolia; D3, pre-treatment value on day 3; D7, post-treatment value on day 7.