Table 4.

Body weight, rectal temperature, and packed cell volume of P. berghei-infected mice treated with hydroalcoholic leaves extract of C. latifolia in the prophylactic test.

GRP	Bodyweight			Rectal temperature			Packed cell volume
	D0	D4	% Change	D0	D4	% Change	D0	D4	% Change
DW	25.74 ± 0.49	22.40 ± 0.66	−13.00 ± 1.53	36.80 ± 0.25	31.58 ± 0.18	−14.18 ± 0.28	57.11 ± 1.22	49.14 ± 1.64	−14.05 ± 1.07
CQ	26.02 ± 0.61	26.50 ± 0.53	1.88 ± 0.43a3	36.84 ± 0.12	36.68 ± 0.11	−0.4389 ± 0.13a3	58.74 ± 0.21	58.23 ± 0.14	−0.8698 ± 0.15a3
CL100	25.75 ± 0.49	23.11 ± 0.52	−10.24 ± 1.02a3b3e3	36.98 ± 0.06	32.48 ± 0.22	−12.17 ± 0.52a3b3e3d3	56.70 ± 0.81	49.98 ± 0.89	−11.87 ± 0.44a1b3e3
CL200	25.80 ± 0.57	23.80 ± 0.54	−7.75 ± 0.67a3b3e3	36.69 ± 0.25	33.76 ± 0.37	−7.99 ± 0.98a3b3e3	57.56 ± 0.63	52.82 ± 0.58	−8.23 ± 0.32a3b3e2
CL400	26.04 ± 0.54	24.90 ± 0.45	−4.35 ± 0.47a3b3	36.82 ± 0.24	35.04 ± 0.16	−4.83 ± 0.37a3b3	58.79 ± 0.35	55.64 ± 0.69	−5.36 ± 1.12a3b3

Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 100 mg/kg; d, to 200 mg/kg; e, to 400 mg/kg; 1, P < 0.05; 2, P < 0.01; 3, P < 0.001; DW, distilled water; CQ, chloroquine; CL, crude extract of Commelina latifolia; D0, pre-treatment value on day 0; D4, post-treatment value on day 4.