Skip to main content
. 2022 Dec 10;8(12):e12045. doi: 10.1016/j.heliyon.2022.e12045

Table 5.

Body weight, rectal temperature, and packed cell volume of infected animals treated with solvent fractions C. latifolia in four-day suppressive test.

Group Weight
Rectal temperature
Packed cell volume
D0 D4 %Change D0 D4 %Change D0 D4 %Change
DW 26.29 ± 0.19 21.84 ± 0.32 −16.90 ± 0.47 36.98 ± 0.05 32.10 ± 0.19 −13.19 ± 0.59 55.08 ± 0.41 46.70 ± 0.66 −15.24 ± 0.68
CQ 25.83 ± 0.51 25.95 ± 0.52 0.47 ± 0.11a3 36.68 ± 0.12 36.57 ± 0.13 −.31 ± 0.04a3 54.67 ± 0.58 54.51 ± 0.57 −.29 ± 0.13
AF100 25.43 ± 0.42 23.12 ± 0.32 −9.07 ± 0.28a3b3e3 36.88 ± 0.06 33.44 ± 0.13 −9.33 ± 0.28a3b3d3e3 54.94 ± 0.61 48.92 ± 0.52 −10.95 ± 0.55a3b3d3e3
AF200 25.00 ± 0.67 23.40 ± 0.58 −6.38 ± 0.19a3b3 36.88 ± 0.12 34.90 ± 0.16 −5.37 ± 0.23a3b3e2 54.96 ± 0.84 50.70 ± 0.83 −7.76 ± 0.25a3b3e3
AF400 25.14 ± 0.88 24.26 ± 0.96 −3.55 ± 0.56a3B2 37.02 ± 0.11 35.88 ± 0.08 −3.08 ± 0.32a3b3 54.60 ± 0.53 52.50 ± 0.63 −3.85 ± 0.46a3b3
TW80 26.07 ± 0.45 22.20 ± 0.37 −14.83 ± 0.48 36.98 ± 0.05 33.18 ± 0.86 −10.28 ± 0.96 55.29 ± 0.66 48.40 ± 0.68 −12.45 ± 0.69
CQ 25.91 ± 0.41 26.16 ± 0.39 0.97 ± 0.22a3 36.80 ± 0.11 36.60 ± 0.24 −.53 ± 0.18a3 55.27 ± 0.29 55.01 ± 0.31 −.47 ± 0.18a3
MF100 25.07 ± 0.43 22.26 ± 0.51 −11.24 ± 0.66a3b3d2e3 36.96 ± 0.67 33.56 ± 0.17 −9.19 ± 0.48a2b3 56.44 ± 0.56 51.40 ± 0.96 −8.96 ± 0.89a1b3e2
MF200 26.14 ± 0.77 24.04 ± 0.62 −7.98 ± 0.65a3b3be3 36.80 ± 0.14 34.80 ± 0.20 −5.43 ± 0.41a1b1 56.78 ± 0.58 53.20 ± 0.66 −6.31 ± 0.28a1b1e1
MF400 25.52 ± 0.88 24.64 ± 0.94 −3.49 ± 0.48a3b3 36.92 ± 0.71 35.74 ± 0.26 −3.19 ± 0.65a2 54.90 ± 0.62 53.20 ± 0.60 −3.08 ± 0.86a2
TW80 26.08 ± 0.65 22.64 ± 0.54 −13.17 ± 0.51 36.96 ± 0.13 32.54 ± 0.29 −11.96 ± 0.63 55.13 ± 0.50 47.40 ± 0.51 −14.00 ± 0.81
CQ 25.76 ± 0.52 26.15 ± 0.57 1.49 ± 0.39a3 36.77 ± 0.49 36.53 ± 0.73 −0.65 ± 0.19a3 56.01 ± 0.74 55.56 ± 0.31 −0.80 ± 0.33a3
CF100 26.11 ± 0.47 23.55 ± 0.28 −9.75 ± 0.95a1b3d1e3 36.66 ± 0.22 33.14 ± 0.22 −9.59 ± 0.69a1b3d1e3 55.64 ± 0.48 49.52 ± 0.50 −11.00 ± 0.19a1b3d2e3
CF200 25.80 ± 0.49 23.88 ± 0.54 −7.46 ± 0.32a3b3fe2 36.84 ± 0.12 34.20 ± 0.19 −7.17 ± 0.30a3b3e2 55.76 ± 0.59 51.49 ± 0.84 −7.67 ± 0.66a3b3
CF400 24.28 ± 0.47 23.28 ± 0.46 −4.12 ± 0.37a3b3 36.98 ± 0.08 35.54 ± 0.23 −3.89 ± 0.41a3b3 54.54 ± 0.77 51.68 ± 0.98 −5.27 ± 0.63a3b3

Data are expressed as mean ± SEM; n = 5; compared to a, negative control; b, CQ25 mg/kg; c, 100 mg/kg; d, 200 mg/kg; e, 400 mg/kg; 1, P < 0.05; 2, P < 0.01; 3, P < 0.001; TW80, 2% Tween80; CQ, chloroquine; AF, aqueous fraction; MF, methanol fraction; CF chloroform fraction; D0, pre-treatment value on day 0; D4, post-treatment value on day 4.