Table 6.
Body weight, rectal temperature, and packed cell volume of infected animals treated with chloroform fraction of C. latifolia in the Rene's test.
Group | Bodyweight |
Rectal temperature |
Packed cell volume |
||||||
---|---|---|---|---|---|---|---|---|---|
D3 | D7 | %Change | D3 | D7 | %Change | D3 | D7 | %CHANGE | |
TW80 | 24.58 ± 0.46 | 20.82 ± 0.36 | −15.27 ± 0.82 | 36.50 ± 0.25 | 31.76 ± 0.11 | −12.98 ± 0.31 | 56.25 ± 0.81 | 48.78 ± 0.90 | −13.29 ± 0.51 |
CQ | 25.76 ± 0.57 | 26.11 ± 0.61 | 1.33 ± 0.26a3 | 36.62 ± 0.20 | 36.28 ± 0.26 | −.93 ± 0.26a3 | 55.36 ± 0.89 | 54.60 ± 0.92 | −1.37 ± 0.49a3 |
CF100 | 26.13 ± 0.47 | 23.68 ± 0.41 | −9.37 ± 0.35a3b3e3 | 36.70 ± 0.24 | 33.08 ± 0.18 | −9.85 ± 0.49a3b3d2e3 | 54.58 ± 0.81 | 49.20 ± 0.73 | −9.84 ± 0.83a2b3d1e3 |
CF200 | 26.20 ± 0.58 | 24.30 ± 0.59 | −7.27 ± 0.52a3b3e3 | 36.82 ± 0.19 | 33.98 ± 0.27 | −7.72 ± 0.36a3b3e3 | 53.72 ± 1.14 | 49.92 ± 1.13 | −7.08 ± 0.49a3b3e2 |
CF400 | 25.37 ± 0.77 | 24.60 ± 0.75 | −3.02 ± 0.32a3b3 | 36.70 ± 0.13 | 35.40 ± 0.16 | −3.54 ± 0.29a3b3 | 57.48 ± 0.37 | 55.22 ± 0.41 | −3.93 ± 0.57a3b1 |
Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 25 mg/kg; d, to 50 mg/kg; e, to 100 mg/kg; 1, P < 0.05; 2, P < 0.01; 3, P < 0.001; TW80, 2% Tween80; CQ, chloroquine; CF, chloroform fraction; D3, pre-treatment value on day 3; D7, post-treatment value on day 7.