Table 7.
Bodyweight, rectal temperature, and packed cell volume of infected animals treated with chloroform fraction of C. latifolia in the prophylactic test.
Group | Bodyweight |
Rectal temperature |
Packed cell volume |
||||||
---|---|---|---|---|---|---|---|---|---|
D0 | D4 | %Change | D0 | D4 | %Change | D0 | D4 | %Change | |
TW80 | 27.46 ± 0.29 | 23.28 ± 0.36 | −15.24 ± 0.59 | 36.44 ± 0.27 | 31.38 ± 0.17 | −13.87 ± 0.52 | 57.11 ± 0.79 | 49.84 ± 1.16 | −12.77 ± 0.91 |
CQ | 26.42 ± 0.49 | 26.70 ± 0.49 | 1.06 ± 0.14a3 | 36.78 ± 0.23 | 36.54 ± 0.23a3 | −0.65 ± 0.23a3 | 57.69 ± 0.43 | 56.96 ± 0.45 | −1.26 ± 0.30a3 |
CF100 | 26.80 ± 0.51 | 24.00 ± 0.45 | −10.43 ± 0.89a3b3d1e3 | 36.33 ± 0.23 | 32.08 ± 0.33 | −11.69 ± 0.82b3d2e3 | 56.49 ± 0.58 | 50.12 ± 0.50 | −11.27 ± 0.4b3d1e3 |
CF200 | 25.66 ± 0.50 | 24.00 ± 0.32 | −6.41 ± 1.03a3b3 | 36.56 ± 0.12 | 33.66 ± 0.39 | −7.93 ± 1.08a3b3 | 56.10 ± 0.69 | 51.40 ± 0.48 | −8.36 ± 0.34a3b3e1 |
CF400 | 26.86 ± 0.59 | 25.54 ± 0.66 | −4.94 ± 0.44a3b3 | 36.48 ± 0.45 | 34.50 ± 0.39 | −5.42 ± 0.28a3b3 | 57.03 ± 0.78 | 53.82 ± 0.66 | −5.59 ± 0.94a3b2 |
Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 25 mg/kg; d, to 50 mg/kg; e, to 100 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; TW80, 2% Tween80; CQ, chloroquine; CF, chloroform fraction; D0, pre-treatment value on day 0; D4, post-treatment value on day 4.