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. 2022 Dec 10;8(12):e12308. doi: 10.1016/j.heliyon.2022.e12308

Table 1.

Summary of neural changes as a result of listening to and/or reciting the Holy Quran.

Author Brainwaves Brain Areas Neuroimaging Methods Quranic Stimuli Non-Quranic Stimuli Analysis Main Findings Author conclusions
Abdullah and Omar (2011) [42] Alpha and beta Frontal, Parietal, Temporal and Occipital EEG (20 electrodes) Not stated which chapter and verse Hard music Analysis was done using Compumedics nexus software During listening to Quranic verses, alpha wave magnitude value is increasing compared to beta value. Listening to Quranic verses generates the alpha wave and helps a person to be in a relaxed condition
Zulkurnaini et al. (2012) [10] Alpha Not stated EEG (not stated how many electrodes) Quran (36:1–83) Pachelbel's
Canon D major (classical music)
Waveware program was used to show the brainwaves response. Alpha band power during listening to Quranic verses is greater compared to classical music Listening to Quranic verses can result in a more relaxing and alert condition compared to classical music
Kamal et al. (2013) [39] Alpha Parietal EEG (20 electrodes) Quran (39:20–31) Excerpt from a novel called Jendela Hati pages 45-46 EEG data were analyzed by using FFT algorithm PSD of alpha band is higher during reciting Quran than reading a book Reciting the Quran leads to a state of resting and calming mind.
The Quran can become a tool for meditation, reduces stress and induce the calming mind
Taha Alshaikhli et al. (2014) [43] Alpha, beta, gamma Frontal EEG (4 electrodes) and ECG Quran (25:1–77) Wintersun entitled ‘Death and the Healing’ (hard music) EEG data were analyzed using KDE and MLP. Alpha waves elicit higher for most subjects when listening to Quranic verses and all subjects had higher gamma wave activity while listening to Quranic verses as opposed to music Listening to Quranic verses causes the subjects to be more relaxed. The ECG signal is smoother while listening to Quranic verses, reflecting the calmness of the subjects
Vaghefi et al. (2015) [28] Alpha and theta Frontal, parietal and occipital EEG (13 electrodes) Quran (49:1–29) & Quran (25:1–57) Positive semantic Arabic text EEG data were analyzed by using FFT algorithm Listening to Quran stimuli consciously increased alpha and theta power Listening to Quranic verses consciously causes the subjects to be more relaxed, which can be related to their religious beliefs
Mohd Nasir and Wan Mahmud (2015) [44] Alpha and beta Not stated Not stated Not stated which chapter and verse Light, Rock, Mozart and Jazz EEG data were analyzed using Powerlab software Alpha and beta waves increased when listening to Rock, Mozart and Quranic verses Listening to Quranic verses increased attention as shown by the increase of alpha and beta waves
Ab Rani et al. (2015) [57] Theta Frontal, midline, temporal, parietal and occipital Simultaneous EEG (61 channels) and MEG (306 sensors) Quran (2:255) with various styles of recitation Hare Krishna chanting, Monochord, Arabic poem, Arabic news Only EEG data were analyzed by using FFT algorithm, SPM8 software Theta band appear highest in the right frontal cortex when listening to Quran stimuli compared to others Listening to Quranic verses increases the theta responses more readily compared with non-Quranic rhythms. It also elicits calming effect to the listeners hence paving the way to be one of the methods in music therapy
Al-Galal and Alshaikhli (2017) [63] Alpha and Beta Frontal and parietal 19-channel EEG signal Verses from the Quran chapters; 36, 94, 112-114 Mozart Music K448 Data were analyzed using BrainMarker software Alpha magnitude is higher than the beta magnitude when listening to the Quranic verses. While the alpha and beta magnitudes are almost equal for music. Listening to Quranic verses increases the alpha magnitude reflecting the calmness and relaxation of the subjects
Shab et al. (2017) [64] Theta Frontal, midline, temporal, parietal and occipital Simultaneous EEG (61 channels) and MEG (306 sensors) Quran (2:255) with various styles of recitation Not applicable Only EEG data were analyzed by using FFT algorithm Highest theta power was dominant at the left frontal region Listening to Quranic verses increase positive emotions
Samhani et al. (2018) [65] Alpha Frontal, midline, temporal, parietal and occipital EEG (128 channels electrode – 19 electrodes were chosen) Quran (1: 1–7) Arabic news EEG data were analyzed using FFT in BESA software Listening to Quranic verses decreased the alpha power at the right inferior frontal and middle temporal Listening to Quranic verses filter the intrusive memory, giving more positive emotion and cognition
Irfan et al. (2019) [66] Alpha & beta Frontal & occipital EEG (2 electrodes, frontal & occipital) Quran (55: 25–40) Morning light by Serenity Studio (soft music) EEG was analyzed using Power-Lab EEG showed that Quran generates comparatively higher amplitudes of alpha than beta waves. Listening to Quranic verses elicits the calmness and relaxation effect shown by an increased in alpha power and mild reduction in diastolic blood pressure in older subjects
Jalaudin and Mohammed Amin (2019) [67] Alpha Parietal EEG (256 channels electrode – 14 electrodes were chosen) Not stated which verse and chapter Not stated what kind of music Spectral analysis was done using MATLAB software Higher alpha power was observed during listening to Quranic verses Listening to Quranic verses influences the relaxation of the mind
Samhani et al. (2022) [68] Beta Occipital EEG (128 channels electrode – 19 electrodes were chosen) Quran (1: 1–7) Arabic news Power spectrum was extracted by FFT using the EGI system Left occipital area showed a significant decrease in beta power when listening to the Quranic verses Listening to Quranic verses activates the oscillatory neural network associated with visual-mental imagery

Note:

ECG = Electrocardiography, FFT = Fast Fourier Transform, PSD = Power Spectral Density, KDE = Kernel Smoothing Density Estimate, MLP = Multi-layer Perceptron.