WYP promoted the polarization of M2 microglia and promoted the secretion of anti-inflammatory factors. (a) WB detected the protein content of Iba-1, Arg-1 and iNOS in the brain. (b) ELISA was used to detect the content of IL-6, IL-1β, IL-10 and TGF-β in the brain. (c) Observed the expression of Iba-1 in the middle of the corpus callosum by immunofluorescence staining. The results represent the mean ± SD. Compared with Control group, ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Compared with CPZ group, △p < 0.05, △△p < 0.01, △△△p < 0.001, △△△△p < 0.0001.