Table 3.
Impact of different maternal features on the risk of ischaemic heart disease (IHD), stroke and myocardial infarction (MI) in women with a history of pre-eclampsia, followed in 1969–2019
| n | IHD HR (95% CI) |
MI HR (95% CI) |
Stroke HR (95% CI) |
||
| Type of pre-eclampsia | Without severe features | 25 814 (81.5%) | 1.00 | 1.00 | 1.00 |
| With severe features or eclampsia | 5874 (18.5%) | 1.15 (1.04 to 1.27) | 1.19 (1.01 to 1.40) | 1.26 (1.12 to 1.41) | |
| Eclampsia | No | 30 681 (96.8%) | 1.00 | 1.00 | 1.00 |
| Yes | 1007 (3.2%) | 0.85 (0.68 to 1.07) | 0.80 (0.54 to 1.19) | 1.15 (0.91 to 1.45) | |
| Recurrence of pre-eclampsia | No | 27 506 (86.8%) | 1.00 | 1.00 | 1.00 |
| Yes | 4180 (13.2%) | 1.30 (1.16 to 1.45) | 1.32 (1.09 to 1.60) | 1.30 (1.14 to 1.47) | |
| Number of fetuses in the index pregnancy | Singleton | 30 862 (78.4%) | 1.00 | 1.00 | 1.00 |
| Twins | 826 (21.6%) | 0.83 (0.62 to 1.09) | 0.77 (0.49 to 1.22) | 0.73 (0.51 to 1.03) | |
| Age at index day (years) | <24 | 7053 (22.3%) | 1.06 (0.94 to 1.20) | 1.08 (0.87 to 1.36) | 1.34 (1.17 to 1.52) |
| ≥24 | 24 635 (77.7%) | 1.00 | 1.00 | 1.00 | |
| County | Southern or western | 22 340 (70.5%) | 1.00 | 1.00 | 1.00 |
| Northern or eastern | 9348 (29.5%) | 1.31 (1.20 to 1.42) | 1.29 (1.11 to 1.49) | 1.12 (1.01 to 1.24) |