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. 2022 Dec 23;7(1):e001180. doi: 10.1136/bmjophth-2022-001180

Table 2.

Summary of the change in clinical parameters in the T&E and mT&E groups between baseline and 36 months

T&E group
(n=135 eyes)
mT&E group
(n=119 eyes)
P value*
Increase in BCVA of ≥15 ETDRS letters, n (%) 31 (23) 30 (25.2) 0.39
Decrease in BCVA of ≥15 ETDRS letters, n (%) 29 (21.5) 21 (17.7) 0.43
No of injections per year, mean±SD 7.9±2.9 8.1±2.3 0.55
Change in CPT, median (IQR) −106 (185.0) −69.5 (133.3) 0.61
Change in CST, median (IQR) −65 (136.5) −56 (146.25) 0.55
No fluid at the final visit, n (%) 36 (26.7) 45 (37.8) 0.06

*Calculated using Student’s t-test, Wilcoxon signed-rank test or Fisher’s exact test.

BCVA, best-corrected visual acuity; CPT, central point thickness; CST, central subfield thickness; ETDRS, Early Treatment for Diabetic Retinopathy Study; mT&E, modified treat-and-extend; T&E, treat-and-extend.