Table 5.
Characteristics of patients with AATD diagnosed during the period 1 January 2000–31 December 2018
| N | % | |
| Total | 1029 | 100 |
| Females | 476 | 46.3 |
| Males | 553 | 53.7 |
| Age (years) | ||
| ≤12 | 113 | 11.0 |
| 13–18 | 25 | 2.4 |
| 19–24 | 18 | 1.7 |
| 25–34 | 61 | 5.9 |
| 35–44 | 143 | 13.9 |
| 45–54 | 204 | 19.8 |
| 55–64 | 236 | 22.9 |
| ≥65 | 229 | 22.3 |
| Charlson Comorbidity Index score at Dx date | ||
| 0 | 417 | 40.5 |
| 1–2 | 465 | 45.2 |
| ≥3 | 147 | 14.3 |
| Lung diseases | ||
| No | 354 | 34.4 |
| Yes | 675 | 65.6 |
| Emphysema | ||
| No | 676 | 65.7 |
| Yes | 353 | 34.3 |
| Asthma | ||
| No | 832 | 80.9 |
| Yes | 197 | 19.1 |
| Other COPD | ||
| No | 440 | 42.8 |
| Yes | 589 | 57.2 |
| Bronchitis | ||
| No | 1011 | 98.3 |
| Yes | 18 | 1.7 |
| Other chronic lower respiratory disease | ||
| No | 1021 | 99.2 |
| Yes | 8 | 0.8 |
| Bronchiectasis | ||
| No | 972 | 94.5 |
| Yes | 57 | 5.5 |
| Liver disease | ||
| No | 918 | 89.2 |
| Yes | 111 | 10.8 |
| Lung and liver disease | ||
| No | 975 | 94.8 |
| Yes | 54 | 5.2 |
AATD, alpha-1 antitrypsin deficiency; COPD, chronic obstructive pulmonary disease; Dx, diagnosis.