Fig. 2.

Effects of LPS alone or in combination with fluoxetine on cell viability in RAW 264.7 macrophages (A). Cells were treated with LPS (1 μg/ml) alone or with increasing doses of fluoxetine (5, 10 or 20 µg/ml) for 24 or 48 h. Levels of IL-6 (B), IL-1β (C) and TNF-α (D) in RAW 256.7 macrophages treated with LPS (1 μg/ml) alone or in combination with fluoxetine (5, 10 or 20 μg/ml) for 24 h. Values are expressed as mean + SEM. All data are from three separate experiments in triplicate. *p < 0.05 statistically significant compared with control, ^###p < 0.001 compared with LPS alone