Table 1.

Definitions of high-risk non-muscle-invasive bladder cancer according to the American and European Urologic Associations

American Urological Association	European Urologic Association
• Carcinoma in situ • High-grade T1 tumors • Recurrent or multifocal or large (> 3 cm) high-grade Ta tumors • Any tumor following BCG failure • Lymphovascular invasion or non-urothelial histology • High-grade tumor involving prostatic urethra	• Carcinoma in situ • Any high-grade tumor • Any T1 tumor • Multiple, recurrent, and large low-grade Ta tumors
	Highest risk: • T1 HG with CIS • Multiple, large, or recurrent T1 high-grade tumors • T1 with CIS in prostatic urethra • Some variant histology or lymphovascular invasion