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Closeness centrality highlights the NTD, CT0, CT1, and CT2 domains
(A–C) Structural representation of the SARS-CoV-2 spike protein in the one-up conformation of the G forms colored by the closeness centrality. This measure is also presented broken down by protein region (B) and by individual residues ranked from highest to lowest (C), for the D and the G form, and for the all-down and the one-up conformations.
