Fig. 2.

A Profile plot of two patient classes identified according to several ventilatory variables at first day of invasive mechanical ventilation using a latent mixture analysis. Values show means in each variable used for classification for each class (after normalization, Z-scores). The largest differences are observed in airway pressures, whereas there are no differences in respiratory rate. B Discharge from the intensive care unit (ICU) alive and spontaneously breathing for each patient class. C Hospital mortality for each patient class. D Hazard ratios for mortality obtained from a marginal structural model addressing the time-dependent changes in each variable