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. 2022 Dec 26;10:240. doi: 10.1186/s40168-022-01442-5

Table 1.

Associations between future early childhood caries case status and sociodemographic and behavioral measures, among pre-incident children from Appalachia

~2-month visita ~12-month visita ~24-month visita
Case, N = 991 Control, N = 911 p value2 Case, N = 891 Control, N = 811 p value2 Case, N = 731 Control, N = 691 p value2
 Child's race 0.8 0.8 0.3
 Bi- or multi-racial 10 (10%) 10 (11%) 8 (9.0%) 8 (9.9%) 5 (6.8%) 8 (12%)
 White 89 (90%) 81 (89%) 81 (91%) 73 (90%) 68 (93%) 61 (88%)
Child's sex > 0.9 > 0.9 0.7
 Female 48 (48%) 44 (48%) 45 (51%) 41 (51%) 36 (49%) 32 (46%)
 Male 51 (52%) 47 (52%) 44 (49%) 40 (49%) 37 (51%) 37 (54%)
Site 0.6 0.7 0.7
 Pennsylvania 45 (45%) 45 (49%) 37 (42%) 36 (44%) 37 (50%) 37 (54%)
 West Virginia 54 (55%) 46 (51%) 52 (58%) 45 (56%) 37 (50%) 32 (46%)
Currently breastfed 0.07 0.2 > 0.9
 Currently breastfed 49 (49%) 57 (63%) 21 (24%) 27 (33%) 4 (5.5%) 4 (5.8%)
 Not currently breastfed 50 (51%) 34 (37%) 68 (76%) 54 (67%) 69 (95%) 65 (94%)
Maternal report of child antibiotics within 3 months prior to visit 8 (8.1%) 8 (8.8%) 0.9 24 (27%) 18 (22%) 0.5 20 (27%) 23 (33%) 0.4
Count of primary teeth erupted 0.0 (0.3) 0.0 (0.0) 0.2 6.1 (3.0) 6.1 (2.8) 0.9 16.4 (1.9) 16.0 (1.8) 0.12
Delivery 0.5 0.7 0.4
 C-section 35 (36%) 28 (31%) 33 (38%) 28 (35%) 28 (39%) 22 (32%)
 Vaginal 63 (64%) 63 (69%) 55 (62%) 53 (65%) 44 (61%) 47 (68%)
 Not reported 1 0 1 0 1 0
Maternal education reported at prenatal visit < 0.001 <0.001 < 0.001
 Associates degree or higher 33 (33%) 57 (63%) 28 (31%) 51 (63%) 30 (41%) 48 (70%)
 High school degree or less 66 (67%) 34 (37%) 61 (69%) 30 (37%) 43 (59%) 21 (30%)
In the past 7 days, about how often did your child drink fruit juice (juice composed of 100% fruit juice)? 0.8 0.003 0.04
 Never or once 64 (94%) 47 (96%) 32 (37%) 53 (65%) 12 (17%) 21 (31%)
 Every few days 0 (0%) 0 (0%) 21 (24%) 10 (12%) 13 (19%) 20 (29%)
 Once a day 1 (1.5%) 1 (2.0%) 16 (18%) 10 (12%) 20 (29%) 11 (16%)
 Several times a day 3 (4.4%) 1 (2.0%) 18 (21%) 8 (10%) 24 (35%) 16 (24%)
 Missing or not reported 31 42 2 1 4 1
Child’s teeth brushed/wiped?
 No 1 (100%) 1 (100%) 8 (9.4%) 12 (15%) 0.3 1 (1.4%) 1 (1.4%) > 0.9
 Yes, with toothpaste 35 (41%) 24 (30%) 65 (94%) 65 (94%)
 Yes, without toothpaste 42 (49%) 43 (54%) 3 (4.3%) 3 (4.3%)
 Missing or not reported 98 90 4 2 4 0

1 Mean (SD); n (%)

2 Wilcoxon rank sum test; Fisher's exact test; Pearson’s chi-squared test

a Includes duplicate records for 1 child selected as a control at 36 months and a case at 60 months, and 1 child selected as a control for both 36 and 60 month risk sets. Excludes samples from children diagnosed as a case at that visit and their corresponding risk-set controls (N = 6 at 12 months, N = 37 at 24 months)