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. 2022 Dec 16;33:101413. doi: 10.1016/j.bbrep.2022.101413

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© 2022 The Authors. Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 1 — Prevalence of anti-IA-2 and ZnT8 autoantibodies in a cohort of 66 patients with established type 1 diabetes. Patients with confirmed type 1 diabetes were assessed for autoantibodies against the intracellular domain of IA-2 (A), and ZnT8 (B) using commercial ELISA assays (RSR Limited, Cardiff UK). Antibodies to IA-2 were present in individual serum samples from 9 of 66 patients, with individual serum samples from 10 patients containing anti-ZnT8 autoantibodies. Serum samples were assessed in triplicate. Assay cut offs for positivity were determined by standards and controls as per manufacturers instructions, and indicated on the figures by dotted lines. Individual points represent mean OD values for individual patient serum samples.