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(a) Serum creatinine assay (n = 5). (b) BUN assay (n = 5). (c) (d) Histological changes in the renal cortex by HE staining and tissue injury scores at 24 h (n = 5). LP, Low power field; HP, High power field. (e) ELISA analysis showing the expression of TNF-α in serum at 24 h (n = 5). (f) ROS level of kidney tissue by DHE fluorescent probe at 24 h (n = 5). (g) Organ toxicity detection of RvD1 at 7 days (n = 5). The data are presented as the mean ± SD ∗∗P < 0.01, ∗∗∗P < 0.001.
