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. 2021 Feb 6;34(4):441–447. doi: 10.4103/tcmj.tcmj_264_20

Table 4.

Treatment outcomes among patients with overactive bladder who failed the initial overactive bladder medication and switched to a different mode of medication*

Mode of switch of OAB medication n Successful, n (%) Failure, n (%) P
Switch OAB medication From solifenacin to mirabegron 50 mg QD 5s1 28 (54.9) 23 (45.1) 0.181
From mirabegron to solifenacin 5 mg QD 47 32 (68.1) 15 (31.9)
Solifenacin 5 mg+mirabegron 25 mg Switch to solifenacin 5 mg QD alone 11 6 (54.5) 5 (45.5) 0.084
Switch to mirabegron 50 mg alone 16 14 (87.5) 2 (12.5)
Add-on≥2 OAB medications From solifenacin to add-on≥2 anti-M 27 14 (51.9) 13 (48.1) 0.357
From mirabegron to add-on≥2 anti-M 33 21 (63.6) 12 (36.4)
Total 185 115 (62.2) 70 (37.8)

*Excluding 65 patients who failed the initial medication but did not switch to other mode of treatment. Anti-M: antimuscarinic agent, OAB: Overactive bladder