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. 2022 Mar 4;34(4):456–461. doi: 10.4103/tcmj.tcmj_258_21

Table 7.

Comparison of serum homocysteine levels with different genotypes

Genes 1/1a 1/2b 2/2c F P
MTHFR C677T 15.7±6.3 15.2±4.5 13.25±3.7 0.38 0.69
MTHFR A1298C 15.14±5.7 17.44±5.8 - 2.13 0.15
MTR A2756G 14.39±5.9 16.17±5.3 18.03±8.07 1.7 0.19
MTRR A66G 16.33±4.5 15.20±5.6 15.68±6.15 0.15 0.86
RFC I G80A 17.02±5.4 14.45±6.2 16.19±4.9 2.1 0.13
CBS844ins68 15.56±6.1 15.36±5.2 - 0.01 0.92

MTHFR: Methylenetetrahydrofolate reductase, MTR: Methionine and enzyme methionine synthase, MTRR: Methionine synthase reductase, RFC 1: Reduced folate carrier 1, CBS: Cystathionine-β-synthase, a: Homozygous wild; b: Heterozygous mutant; c: Homozygous mutant