Table 7.
Comparison of serum homocysteine levels with different genotypes
Genes | 1/1a | 1/2b | 2/2c | F | P |
---|---|---|---|---|---|
MTHFR C677T | 15.7±6.3 | 15.2±4.5 | 13.25±3.7 | 0.38 | 0.69 |
MTHFR A1298C | 15.14±5.7 | 17.44±5.8 | - | 2.13 | 0.15 |
MTR A2756G | 14.39±5.9 | 16.17±5.3 | 18.03±8.07 | 1.7 | 0.19 |
MTRR A66G | 16.33±4.5 | 15.20±5.6 | 15.68±6.15 | 0.15 | 0.86 |
RFC I G80A | 17.02±5.4 | 14.45±6.2 | 16.19±4.9 | 2.1 | 0.13 |
CBS844ins68 | 15.56±6.1 | 15.36±5.2 | - | 0.01 | 0.92 |
MTHFR: Methylenetetrahydrofolate reductase, MTR: Methionine and enzyme methionine synthase, MTRR: Methionine synthase reductase, RFC 1: Reduced folate carrier 1, CBS: Cystathionine-β-synthase, a: Homozygous wild; b: Heterozygous mutant; c: Homozygous mutant