Table 2.
Values of hemodynamic variables at baseline, on iNO and ivS
| Hemodynamic variables (N = 44) | Baseline | iNO | ivS | p Value |
|---|---|---|---|---|
| sPAP, mmHg | 87.2 ± 20.6 | 78.3 ± 21.8 | 74.1 ± 22.1 | 0.007 |
| dPAP, mmHg | 40.0 ± 14.4 | 35.1 ± 14.2 | 33.1 ± 13.3 | 0.111 |
| mPAP, mmHg | 57.9 ± 15.8 | 51.7 ± 16.1 | 49.0 ± 15.2 | 0.008 |
| sAP, mmHg | 125.5 ± 22.5 | 122.9 ± 24.6 | 116.3 ± 20.9 | <0.001 |
| dAP, mmHg | 67.9 ± 13.3 | 68.6 ± 13.4 | 65.6 ± 11.6 | 0.027 |
| mAP, mmHg | 87.8 ± 15.5 | 86.8 ± 16.3 | 82.6 ± 13.7 | 0.068 |
| Qpi, L/min/m2 | 3.8 ± 3.1 | 3.8 ± 2.9 | 3.8 ± 2.5 | 0.726 |
| Qsi, L/min/m2 | 2.7 ± 1.1 | 2.8 ± 0.9 | 2.7 ± 0.9 | 0.401 |
| Qp:Qs | 1.4 ± 0.7 | 1.4 ± 0.8 | 1.5 ± 0.9 | 0.480 |
| PVRI, Wu·m2 | 17.7 ± 10.6 | 14.8 ± 9.5 | 14.0 ± 8.9 | 0.139 |
| SVRI, Wu·m2 | 31.4 ± 11.4 | 29.1 ± 9.7 | 28.5 ± 10.5 | 0.517 |
| PVRI:SVRI | 0.6 ± 0.3 | 0.5 ± 0.3 | 0.5 ± 0.3 | 0.944 |
| PACI, mmHg/ml/min/m2 | 0.9 ± 0.7 | 1.0 ± 0.8 | 1.1 ± 0.7 | 0.230 |
| mRA, mmHg | 6.4 ± 3.0 | 5.9 ± 2.6 | 5.7 ± 2.4 | 0.130 |
| mLA, mmHg | 8.3 ± 3.0 | 8.0 ± 3.2 | 8.0 ± 3.3 | 0.884 |
| sPAP:sAP | 0.7 ± 0.2 | 0.7 ± 0.2 | 0.7 ± 0.2 | 0.914 |
| mPAP:mAP | 0.7 ± 0.2 | 0.6 ± 0.2 | 0.6 ± 0.2 | 0.645 |
Note: Values as mean ± SD.
Abbreviations: dAP, diastolc aortic pressure; dPAP, diastolic pulmonary artery pressure; iNO, inhaled nitric oxide; ivS, intravenous sildenafil; mAP, mean aortic pressure; mLA, mean left atrial pressure; mPAP, mean pulmonary artery pressure; mRA, mean right atrial pressure; PACI, indexed pulmonary artery capacitance; PVRI, indexed pulmonary vascular resistance; Qp, pulmonary blood flow; Qpi, indexed pulmonary blood flow; Qs, systemic blood flow; Qsi, indexed systemic blood flow; sAP, systolic aortic pressure; sPAP, systolic pulmonary artery pressure; SVRI, indexed systemic vascular resistance; Wu, wood units.