Table 2.

Scoring system for inflammation-associated histological changes in the colon.

Score	Inflammation	Crypt damage	Ulceration	Edema
0	No infiltrate	None	None	Absent
1	Occasional cells limited to submucosa	Some crypt damage, spaces between crypts	Small, focal ulcers	Present
2	Significant presence of inflammatory cells in submucosa limited to focal areas	Larger spaces between crypts, loss of goblet cells, some shortening of crypts	Frequent small ulcers
3	Infiltrate is present in both submucosa and lamina propria, limited to focal areas	Large areas without crypts, surrounded by normal crypts	Large areas lacking surface epithelium
4	A large amount of infiltrate in the submucosa, lamina propria, and surrounding blood vessels, covering large areas of mucosa	No crypts
5	Transmural inflammation (mucosa to muscularis)