Fig. 3.

Inverse correlation between CD4⁺nadir and latent reservoir volume at 30 days after primary infection in model simulations. a) An inverse correlation between the latent reservoir and CD4 + T cell nadir exists if the latent reservoir proliferates ($r_L\ne 0$) (p < 0.05). Each color corresponds to model fitting to one of twelve participants in the FRESH cohort. b) Correlation between the latent reservoir and CD4 + T cell nadir disappears if the latent reservoir does not proliferate ($r_L=0$). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)