Fig. 5.

The module–trait relationships of the WGCNA of SN proteome data. The module–trait relationships of WGCNA of the SN proteome data were presented in the form of a heatmap. The Pearson correlations between 26 protein cluster modules and four traits composed of diagnosis, age, sex, and PMD were calculated and colored on a scale of 1 (positive correlation) to −1 (negative correlation). A protein cluster module was generated by collecting proteins with similar expression patterns across the samples. The correlation values are shown at the top of each box, and the p values are shown on the bottom of each box inside the parenthesis. PMD, postmortem delay; SN, substantia nigra; WGCNA, weighted gene coexpression network analysis.