Table 1.

Information on the SN samples used in the discovery study

No.	Diagnosis	Age at death	Sex	Race	PMD (h)	CERAD
1	PD with dementia, AD definite	64	M	W	21	C
2	PD with dementia, AD probable	82	F	W	5	B
3	PD with dementia, AD probable	80	M	W	13	B
4	PD, no dementia	73	F	W	6	A
5	PD with dementia, LBD neocortical	84	M	W	5	0
6	PD, LBD neocortical, AD	74	M	W	19	C
7	PD, LBD limbic	95	F	W	12	0
8	PD with dementia	76	M	W	19	0
9	PD with dementia	76	M	W	17	0
10	PD with dementia, AD probable	85	F	W	11	B
11	PD, no dementia	86	M	W	22.5	0
12	PD with dementia, AD probable	83	F	W	4	B
13	PD with dementia	60	M	W	15.5	0
14	PD with dementia, AD definite	80	F	W	16	C
15	PD with dementia, AD probable	85	M	W	14	B
16	HC, NFT, & frequent tau neurites in HP (age-associated tau pathology)	76	M	W	25	0
17	HC, moderate Tau+ neurites in HP and ERC	67	M	W	37	0
18	HC, GVD in HP, Tau NFT and neurites in ERC (Braak I)	71	F	B	37	0
19	HC, rare NFT in ERC, no amyloid plaques, old contusions (Braak I)	81	M	W	26	0
20	HC, rare NFTs in ERC and HP, no amyloid plaques (Braak II)	80	F	W	37	0
21	HC, no Tau or amyloid lesions	67	M	W	25	0
22	HC, rare Tau+ neurites in HP, no amyloid plaques	67	M	W	8	0
23	HC, NFT in ERC but not in HP, no amyloid plaques	71	F	W	57	0
24	HC, rare NFT in HP and ERC (Braak II)	66	M	B	25	0
25	HC, NFT in HP and ERC, no amyloid plaques (Braak II)	77	F	W	33	0
26	HC, NFT in ERC but none in HP	80	M	B	21	0
27	HC, mild NFT in HP and ERC, no amyloid plaques (Braak II)	87	F	W	7	0
28	HC, NFT in HP, ERC and ITC, plaques in temporal lobe (Braak III)	90	F	B	22	A
29	HC, no NFT, no amyloid plaques	60	M	W	16	0
30	HC, NFT in ERC and HP, few amyloid plaques in HP	87	F	W	35	A

Abbreviations: AD, Alzheimer’s disease; B, black; CERAD, Consortium to Establish a Registry for Alzheimer’s Disease; ERC, entorhinal cortex; F, female; GVD, granulovacuolar degeneration; HP, hippocampus; ITC, inferior temporal cortex; LBD, Lewy body dementia; M, male; NFT, neurofibrillary tangle; W, white