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The function of the glymphatic pathway was impaired after tMCAO but rescued by pretreatment with XFZYD. (A) Representative images of coronal brain sections showing FITC-D3 distribution within the brain at 30 min (Scale bar, 1 mm). (B) Quantitative analysis of the fluorescence intensity and penetration area of data A (n = 4 mice per group, *p < 0.05 vs. the sham group, # p < 0.05 vs. the tMCAO group). CSF, Cerebrospinal fluid; FITC-D3, fluorescein isothiocyanate-conjugated dextran.
