Table 3.

Risk Factors for Decreased IOP among Survivors of Ebola Virus Disease

Factor	IOP for Participants with Factor (Median, Interquartile Range)	IOP for Participants Without Factor (Median,Interquartile Range)	Effect Estimate, Adjusted for Age and Sex (Mean Difference)	95% ConfidenceInterval	P Value
	Physical Examination Findings
Afferent pupillary defect	14.6 (9.1–17.4)	12.4 (10.4–14.5)	+3.57	(1.58, 5.57)	< 0.001
Keratic precipitates	12.1 (10.5–13.9)	12.4 (10.4–14.5)	−0.5	(−1.72, 0.71)	0.42
Synechiae	10.7 (9–13.9)	12.4 (10.5–14.5)	−1.12	(−2.56, 0.32)	0.13
Anterior chamber cells	11.6 (9.6–13)	12.4 (10.4–14.5)	−0.85	(−2.35, 0.65)	0.27
Vitreous cell	11 (9–12.8)	12.5 (10.5–14.7)	−1.61	(−2.69, −0.54)	0.003
Macular scar	12.7 (10.5–14.6)	12.4 (10.4–14.5)	+0.25	(−0.72, 1.22)	0.62
Peripheral retinal scar	12.5 (9.7–13.5)	12.4 (10.4–14.5)	−0.74	(−2.13, 0.64)	0.29
Cataract	12.8 (10.5–15)	12.4 (10.4–14.5)	+0.44	(−0.51, 1.39)	0.36
OCT
Intraretinal fluid cysts	11.8 (10.5–12.8)	12.5 (10.4–14.5)	−0.42	(−1.83, 0.99)	0.56
Vitreous opacities	11.8 (10–14)	12.5 (10.5–14.7)	−0.68	(−1.34, −0.02)	0.045
Epiretinal membrane	11.8 (10.5–14)	12.8 (10.5–15)	−0.26	(−1.94, 1.43)	0.77
Diagnoses
Inactive Uveitis	12 (10.5–14.4)	12.4 (10.5–14.5)	−0.49	(−1.21, 0.24)	0.19
Active Uveitis	11.2 (9.5–12.8)	12.5 (10.5–14.5)	−1.21	(−2.5, 0.07)	0.07

Eyes with an afferent pupillary defect had a significantly higher median IOP. IOP measured during the baseline ophthalmic evaluation was relatively lower in participants with vitreous cell on clinical examination and vitreous opacities identified through OCT. Data are presented as median and interquartile range, with mean difference and 95% confidence interval. Estimates are adjusted for age and sex. Boldface indicates statistical significance.

IOP = intraocular pressure.