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. 2022 Dec 14;29:101765. doi: 10.1016/j.ajoc.2022.101765

Table 1.

Previous cases of a tectonic posterior lamellar keratoplasty graft in managing impending or actual perforation.

Author Year Region Number of cases Description Type of procedure Follow up Outcomes Final VA
Graue-Hernandez4 2012 Mexico 1 Corneal thinning secondary to dry eye. A tectonic DSAEK and amniotic membrane graft. 8 months Ocular surface healed quickly, and re-epithelization occurred over 2 weeks and lasted for follow-up. NA
Nahum5 2016 Israel and Italy 3 Case 1,2: Endothelial decompensation and sterile corneal perforation.
Case 3- an impending corneal perforation.
DSAEK Case 1: 3 months
Case 2: 1 year
Case 3: 1 year
All grafts remained clear throughout the follow-up. Case 1 underwent DALK on DSAEK with improved visual acuity. Case 1–20/30
Case 2–20/60
Case 3–20/400
Okada8 2016 Japan 1 A corneal perforation of undetermined etiology. Partial-thickness corneal button 5 months Seven weeks postoperatively, the corneal defect was closed and lasted for follow-up. 6/6
Jesse6 2017 Switzerland 1 A perforated corneal ulcer due to neurotrophic keratopathy caused by previous recurrent herpetic keratitis. A DSAEK graft. 6 months Re-bubbling was performed the day after and four 10–0 Nylon sutures were placed for 2 weeks those = The long-term follow-up showed stable and transparent cornea. CF due to severe AMD.
Tourkmani7 2020 United Kingdom 4 Case 1- perforation due to exposure keratopathy
Case 2,3- perforation due to herpetic keratitis
Case 4- corneal hydrops secondary to PMD.
Cases 1–3: DSEK Case 4: hemi-DSEK Case 1: 2 months
Case 2:NA
Case 3:NA
Case 4:NA
Case 1–4: Tectonic goal satisfactorily achieved.
Case 4- patient underwent 2 re-floating attempts before anchoring suture placement due to repeated graft detachment.
Case 1-NA, without visual potential.
Case 2-NA
Case 3-NA
Case 4-NA

DSEK; Descemet stripping endothelial keratoplasty, DSAEK; Descemet stripping automated endothelial keratoplasty, BCVA; best-corrected visual acuity, VA; visual acuity, CF; counting fingers, PMD; pellucid marginal degeneration, NA; not available, DALK; deep anterior lamellar keratoplasty.