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. 2022 Aug 9;6(24):6219–6227. doi: 10.1182/bloodadvances.2022008028

Table 3.

Outcomes of patients treated with caplacizumab as initial treatment vs patients not treated with caplacizumab

patients with iTTP treated with caplacizumab as initial treatment (n = 44) patients with iTTP not treated with caplacizumab (n = 78) P
Clinical remission 42/44 (95.5%) 73/78 (93.6%) .6501
 Exacerbation 2/44 (4.5%) 16/78 (20.5%) .023
 Refractoriness 2/44 (4.5%) 11/78 (14.1%) .042
Death 2/44 (4.5%) 6/78 (7.7%) .567

The 2 patients who were refractory to treatment were those who died, although they were different from the other 2 who had an exacerbation.