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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Subst Use Misuse. 2022 Dec 8;58(1):1–10. doi: 10.1080/10826084.2022.2125271

Table 3.

Main Effect and Interaction Effect of Non-Medical Prescription Opioid Use (NMPOU) and Race on Suicidality (n=38,088)

Serious Thoughts of Suicide Have a Plan for Suicide Suicide Attempts
Those With NMPOU Those Without NMPOU OR (95% CI) Those With NMPOU Those Without NMPOU OR (95% CI) Those With NMPOU Those Without NMPOU OR (95% CI)

Non-Medical Prescription Opioid Use b 16.0% 5.5% 1.00 (0.77; 1.30) 7.7% 2.0% 1.24 (0.86; 1.79) 3.9% 0.8% 1.41 (0.84; 2.37)
Have 1 or More Disability b 12.6% 4.2% 1.13 (0.94; 1.37) 5.5% 1.3% 1.28 (1.03; 1.58)* 3.9% 1.3% 1.72 (1.30; 2.29)***
No Disability (Ref) 9.8% 4.1% -- 3.9% 1.3% -- 2.5% 0.7% --
Non-Medical Prescription Opioid Use x Disabled 1.47 (1.01; 2.12)* 1.89 (1.23; 2.92)** 2.57 (1.30; 5.09)**
Pseudo R2 0.34a 0.29a 0.25a
Wald Statistic F Statistic (df) 68.81*** (43, 8) 50.41*** (43, 8) 59.04*** (43, 8)
*

p-value <0.05

**

p-value <0.01

***

p-value <0.001

All analyses controlled for socio-demographics, other substance use (binge drinking, cannabis, heroin, fentanyl, cocaine, crack cocaine, inhalants, hallucinogens, methamphetamine, stimulants, tranquilizers, sedatives), self-rated health, and mental health (past-year major depressive episode, psychological distress, mental health impairment). Estimates from these variables can be furnished upon request.

a

Pseudo R2 was not estimated with survey design weights due to issues of heteroskedasticity. The Pseudo R2 value presented here is unweighted.

b

The main effects reported here in Table 3 are controlling for the interaction effects between NMPOU and disability status. The interaction term (Non-Medical Prescription Opioid Use x Disabled) was statistically significant for all three measures of suicidality, even when controlling for the main effects in this interaction analysis.