TABLE 3.
The comparison between serum 25(OH)D levels and anti-SARS-CoV-2 antibody (anti-SARS-CoV-2 S-RBD IgG and NAb) levels in subjects subgroup by vitamin D3 supplementation daily consumption.
| Vitamin D3 daily supplementation | N | Serum 25(OH)D level (ng/mL) |
S-RBD IgG level (AU/mL) |
NAb level (AU/mL) |
|||
| Categories | Averages, in median [IQR] or mean ± SD | Median [IQR] | Significance | Median [IQR] | Significance | ||
| Yes | 22 | Deficient (<30 ng/mL) | 21.00 ± 5.36 | 91.56 [652.00] | 0.049b | 33.51 [208.67] | 0.066b |
| 61 | Sufficient (≥30 ng/mL) | 52.66 ± 25.99 | 414.07 [1441.83] | 149.71 [410.68] | |||
| No | 25 | Deficient (<30 ng/mL) | 18.94 ± 6.81 | 227.35 [581.67] | 0.357a | 129.03 [250.19] | 0.303a |
| 11 | Sufficient (≥30 ng/mL) | 38.04 ± 6.37 | 102.65 [427.77] | 35.42 [156.24] | |||
aAnalyzed using t-test after transformation.
bAnalyzed using Mann-Whitney U test.
25(OH)D, 25-hydroxy-vitamin D; S-RBD IgG, antibodies against receptor binding domain of SARS-CoV-2 spike protein; NAb, neutralizing antibody; IQR, interquartile range; SD, standard deviation.
Bold value denotes statistical significance.