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. 2022 Dec 16;24:136–152. doi: 10.1016/j.bioactmat.2022.12.010

Fig. 4.

Fig. 4

Deep-penetrating triple-responsive prodrug nanosensitizer Actuates Efficient CRT in PDAC a. Efficient PDAC tumor accumulation, b. GGT-triggered tumor penetration, c. The potential mechanism of GSH/hypoxia dual-responsive drug release and hypoxic chemo-radio sensitization, and d. Representative in vivo bioluminescence images of orthotopic PDAC models treated as indicated [78]. Copyright 2022, John Wiley and Sons.