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. 2022 Dec 5;67:101651. doi: 10.1016/j.molmet.2022.101651

Figure 6.

Figure 6

PPM increases the number of Treg and Th2 lymphocytes in plaques of Ldlr−/−mice. A-B. Immunohistochemistry staining and quantitation of CD3+ (green) T lymphocytes in atherosclerotic lesions of female Ldlr−/− mice. Scale bar = 50 μm. C-D. Immunohistochemistry staining and quantitation of GATA-3+ (green) Th2 lymphocytes in atherosclerotic lesions of female Ldlr−/− mice. Scale bar = 50 μm. E-F. Immunohistochemistry staining of FoxP3+ (green) Treg cells. F. PPM increases the number of Treg cells in plaques of Ldlr−/− mice. Scale bar = 50 μm. For each experiment (n = 6 or 7 in each group), graph data are expressed as mean ± SEM; ∗P < 0.05 by two-sided unpaired t-test.