Figure 7.

PPM decreases the number of blood Ly6C^himonocytes and the ratio of Ly6C^hito Ly6c^Lowmonocytes in female Ldlr^−/−mice. A-B. The representative flow cytometry gating strategies for monocyte subsets, neutrophils, T cells, and B cells in peripheral blood of vehicle alone or PPM treated female Ldlr^−/− mice fed a western diet for 14 weeks are shown. C. There was a reduction in total blood monocytes in PPM versus water treated Ldlr^−/− mice. D. PPM reduced the number of Ly6C^hi monocytes E. PPM did not impact the number of Ly6C ^low monocytes. F. PPM decreased the ratio of Ly6C^hi to Ly6C ^low monocytes. n = 9 in each group. Graph data are expressed as mean ± SEM; ∗P < 0.05 by two-sided unpaired t-test.