Table 2.
Nanostring GeoMx protein targets.
| Protein | Code class | Protein group |
|---|---|---|
| S6 | Control | Housekeepers; all targets |
| Rb IgG | Negative | Background; all targets |
| Ki-67 | Endogenous | Proliferation; all targets |
| CD45 | Endogenous | Total Immune; all targets |
| PD-1 | Endogenous | T cells; checkpoint; T cell activation; all targets |
| CD68 | Endogenous | M2 Macrophage; myeloid; macrophage; all targets |
| GZMB | Endogenous | T cell activation; cytotoxicity; all targets |
| Ms IgG1 | Negative | Background; all targets |
| GAPDH | Control | Housekeepers; all targets |
| Histone H3 | Control | Housekeepers; all targets |
| CTLA4 | Endogenous | T cells; checkpoint; T cell activation; Th cells; all targets |
| PD-L1 | Endogenous | Checkpoint; myeloid activation; all targets |
| Fibronectin | Endogenous | Stroma; fibroblasts; all targets |
| CD20 | Endogenous | B cells; all targets |
| CD4 | Endogenous | T cells; myeloid; Th cells; all targets |
| CD8 | Endogenous | T cells; CD8 T cells; all targets |
| Ms IgG2a | Negative | Background; all targets |
| HLA-DR | Endogenous | Antigen presentation; MHC2; all targets |
| CD3 | Endogenous | T cells; all targets |
| PanCk | Endogenous | Tumor; epithelial; all targets |
| Beta-2-microglobulin | Endogenous | Tumor; antigen presentation; all targets |
| CD11c | Endogenous | DC; myeloid; all targets |
| SMA | Endogenous | Stroma; all targets |
| CD56 | Endogenous | NK cells; all targets |
| Cathepsin L/V/K/H | Endogenous | Protease; all targets |
| TMPRSS2 | Endogenous | Protease; all targets |
| DDX5 | Endogenous | Immune response; all targets |
| ACE2 | Endogenous | Viral receptor; all targets |
| CD27 | Endogenous | T cells; T cell activation; all targets |
| CD80 | Endogenous | Myeloid; myeloid activation; all targets |
| CD40 | Endogenous | Myeloid; myeloid activation; all targets |
| CD44 | Endogenous | T cell activation; all targets |
| CD25 | Endogenous | T cells; T cell activation; Tregs; all targets |
| PD-L2 | Endogenous | Checkpoint; all targets |
| CD127 | Endogenous | T cells; naive and memory; all targets |
| ICOS | Endogenous | T cell activation; all targets |
| CD14 | Endogenous | Myeloid; monocyte; all targets |
| CD45RO | Endogenous | T cells; memory; all targets |
| FOXP3 | Endogenous | T cells; Th cells; tregs; all targets |
| CD34 | Endogenous | Hematopoietic; all targets |
| FAP-alpha | Endogenous | Stroma; fibroblasts; all targets |
| CD163 | Endogenous | M2 Macrophage; myeloid; macrophage; all targets |
| CD66b | Endogenous | Myeloid; neutrophil; all targets |
| CD21 | Endogenous | Custom target; all targets |
| Syndecan-1 | Endogenous | Custom target; all targets |
| CD10 | Endogenous | Custom target; all targets |