Table 2.

Logistic analysis of pCR in HER2-low and HER2-zero patients.

	HER2-low (n = 236)				HER2 zero (n = 89)				Overall (n = 318)
	univariate analysis		multivariate analysis		univariate analysis		multivariate analysis		univariate analysis		multivariate analysis
	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
HER2 status low vs zero	–	–	–	–	–	–	–	–	0.859(0.456–1.616)	0.637	1.038(0.460–2.339)	0.929
ER status positive vs negative	0.193(0.086–0.404)	0.000	0.736(0.185–2.927)	0.664	0.441(0.115–1.386)	0.186	3.494(0.452–27.007)	0.231	0.245(0.126–0.458)	0.000	1.187(0.391–3.599)	0.762
PR status positive vs negative	0.175(0.068–0.396)	0.000	0.289(0.059–1.412)	0.125	0.214(0.032–0.837)	0.051	0.169(0.018–1.577)	0.119	0.186(0.082–0.377)	0.000	0.251(0.069–0.907)	0.035
Ki-67 >20% vs ≤ 20%	9.216(2.695–57.839)	0.003	3.778(0.775–18.429)	0.100	3.797(0.681–71.344)	0.214	0.803(0.045–14.229)	0.881	7.348(2.601–30.806)	0.001	2.935(0.774–11.137)	0.113
AR status positive vs negative	0.128(0.020–0.454)	0.007	0.231(0.048–1.106)	0.067	0.193(0.010–1.108)	0.128	0.150(0.007–3.004)	0.215	0.142(0.034–0.413)	0.002	0.256(0.070–0.937)	0.040
LN status N1-3 vs N0	0.352(0.152–0.852)	0.016	0.300(0.083–1.083)	0.066	1.230(0.284–8.547)	0.803			0.487(0.236–1.054)	0.057	0.325(0.112–0.943)	0.039
T stage T4 vs T1-3	0	0.988			0.739(0.107–3.147)	0.713			0.190(0.030–0.643)	0.024	0.584(0.120–2.858)	0.507
Age	0.974(0.938–1.010)	0.151			0.973(0.924–1.021)	0.266			0.973(0.944–1.002)	0.066
Histological type NST vs Other	1.147(0.360–5.103)	0.834			0.462(0.082–3.548)	0.397			0.883(0.340–2.746)	0.812
Histological type Invasive lobular vs Other	1.133(0.050–11.414)	0.921			0	0.993			0.467(0.023–3.475)	0.513

OR: odds ratio; ER: estrogen receptor; PR: progesterone receptor; AR: androgen receptor; NST: no special type.