TABLE 2.
Secretion of IL-8 by the undifferentiated HT29-18N2 cell line exposed to reactogenic or nonreactogenic cholera vaccine strains
| Strain or treatment | Mean IL-8 concn (pg/ml) ± SEMa
|
|
|---|---|---|
| 4 h (n = 3) | 8 h (n = 3) | |
| 81 | 32.4 ± 0.64 | 1,396 ± 13 |
| 638 | <10 | <10 |
| JBK70 | 32.3 ± 0.6 | 486 ± 3.4 |
| CVD103HgR | <10 | 32.4 ± 0.52 |
| TNF-αb | 13,775 ± 250.1 | ND |
a
Background secretion of IL-8 in unstimulated HT29-18N2 cultures at 8 h was <10 pg/ml. ND, not determined.
b
TNF-α-treated cells were included as a positive control.