Table 1.
Genetic Syndrome | Gene Mutation | Relative Risk of Pancreatic Cancer |
---|---|---|
Peutz-Jeghers syndrome | STK11 | 132 |
Hereditary Pancreatitis | PRSS1 | 69 |
SPINK1 | ||
CTRC | ||
CFTR | ||
Familia atypical multiple mole melanoma | CDKN2A | 13–39 |
Li – Fraumani syndrome | TP53 | 7.3 |
Hereditary breast ovarian cancer syndrome | BRCA1, | 2.26 |
BRCA2 | 3.5–6.2 | |
Lynch Syndrome | MLH1, MSH2, MSH6, PMS2 | 5–9 |
Familia adenomatous polyposis | APC, MUTYH | 4.46 |
Ataxia telangiectasia | ATM | 2.7 |