Figure 13.

Demonstration of nonparametric analysis on synthetic pulsed data. In (a) we show simulated data for a pulsed illumination experiment. It illustrates a trajectory with three system states labeled $s_n$ in blue and the corresponding photon arrivals with the vertical length of the red or green line denoting the lifetime observed in nanoseconds. Here (b) and (c) show the bivariate posterior for the escape rates ${\lambda }_{esc}$ and FRET efficiencies ${ϵ}_{FRET}$. The ground truth is again shown with red dots. The learned posterior using the two system state parametric model (c) combines high FRET states into one averaged system state with a long lifetime. The nonparametric model correctly infers three system states, as shown in (b).