Table S12.
Average cost of treating an adverse event by type and grade
| Adverse event | GRADE 1/2 | GRADE 3/4 | ||
|---|---|---|---|---|
| Cost (€) | Reference | Cost (€) | Reference | |
| Nausea and vomiting | 216.94 | (67) | 216.94 | (67) |
| Constipation/diarrhea | 934.85 | (67) | 1546.37 | (67) |
| Fatigue | 1.23 | (67) | 174.68 | (67) |
| Peripheral edema | - | - | 495.34 | (31) |
| Anemia | 367.36 | (67) | 497.43 | (67) |
| Neutropenia | 272.10 | (67) | 272.10 | (67) |
| Increased ALT | - | - | 1329.37 | (31) |
| Increased AST | - | - | 631.06 | (31) |
| Increased bilirubin | - | - | 1098.37 | (31) |
| Leukopenia | 684.40 | (67) | 1596.91 | (67) |
| Thrombocytopenia | 254.81 | (67) | 924.70 | (67) |
AST: Aspartate transaminase; ALT: Alanine transaminase