Table 4.
Sensitivity and specificity of ultrasonography in the diagnosis of infantile hypertrophic pyloric stenosis based on combined measurements
| Author | Yeara | Casesb | Proportion IHPS | Cut-off value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|---|---|
| Neilson 45 | 1994 | 147 | 0.46 | PMT > 2.5 mm or PCL>15 mm or PD>11 mm | 97.1 | 98.7 | 98.5 | 97.5 | 98.0 |
| Vinycomb 51 | 2021 | 284 | 0.50 | PMT ≥ 3 mm and PCL≥14.5 mm PMT ≥ 3 mm and PCL≥15 mm |
93.1 94.4 |
99.1 99.1 |
99.4 99.3 |
90.6 93.5 |
95.5 96.5 |
| Khatami 28 | 2009 | 84 | 1.00 | PMT > 3 mm and PCL>15 mm | 87.7 | n/e | n/e | n/e | n/e |
| Sivitz 31 | 2013 | 67 | 0.85 | PMT > 3 mm and PCL>17 mm | 100.0 | 100.00 | 100.0 | 100.0 | 100.0 |
| Niedzielski 46 | 2011 | 115 | 0.83 | PMT ≥ 3 mm and/or PCL≥17 mm | 97.9 | 100.0 | 100.0 | 90.5 | 98.3 |
| Frkovic 23 | 2001 | 9 | 1.00 | PMT ≥ 3 mm, PCL≥17 mm and PD≥13 mm with pyloric canal closed | 88.9 | n/e | n/e | n/e | n/e |
| dell'Agnola 12 | 1984 | 17 | 0.82 | PMT > 4 mm or PCL>13 mm or PD>9.9 mm | 100.0 | 100.00 | 100.0 | 100.0 | 100.0 |
| Rollins 15 | 1991 | 100 | 0.49 | PMT ≥ 4 mm and/or PD≥15 mm | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
| Misra 47 | 1997 | 65 | 0.95 | PMT > 4 mm and PCL > 16 mm | 87.1 | 0.00 | 94.7 | 0.00 | 83.1 |
| De Backer 16 | 1994 | 63 | 1.00 | PMT > 4 mm and/or PCL>16 mm | 60.3 | n/e | 100.0 | n/e | n/e |
| Forman 14 | 1990 | 44 | 0.50 | PMT > 4 mm. and/or PCL>16 mm | 88.9 | 100.0 | 100.0 | 90.0 | 94.4 |
| Boneti 48 | 2008 | 30 | 0.93 | PMT ≥ 4 mm and/or PCL>16 mm. | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
| Copeland 49 | 2009 | 32 | 0.78 | PMT ≥ 4 mm and/or PCL≥16 mm | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
| McVay 50 | 2009 | 71 | 0.92 | PMT ≥ 4 mm and/or PCL≥16 mm | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
| Mollitt 13 | 1987 | 54 | 0.58 | PMT > 4 mm MWT and/or PCL>17 mm and/or PD>13 mm | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
IHPS, infantile hypertrophic pyloric stenosis; NPV, negative-predictive value; PCL, pyloric canal length; PD, pyloric diameter; PMT, pyloric muscle thickness; PPV, positive-predictive value.
a
Year published
b
Total number of cases included in the study. PMT stands for pyloric muscle thickness, PCL pyloric canal length and PD pyloric diameter. N/e means not estimable, because there was lack of sufficient data to calculate value and/or value was not reported in publication.