Table 4.

Logistic regression analysis assessing factors impacting the presence of splenic switch-off in each cohort separately and when combined

		Univariate			Multivariate
		N	OR (95% CI)	p-value	N	OR (95% CI)	p-value
AF
	Age	70	1.00 (0.94–1.06)	0.962
	Sex (F = 1)	70	5.23 (1.02–26.74)	0.047*	69	7.67 (1.28–45.90)	0.026**
	Hypertension	70	0.57 (0.22–1.46)	0.240*	69	0.35 (0.11–1.15)	0.084
	Dyslipidaemia	70	2.46 (0.84–7.14)	0.099*	69	4.88 (1.28–18.65)	0.021**
	Haem. Responsee	69	1.85 (0.70–5.13)	0.236*	69	1.59 (0.49–5.10)	0.439
	Symptoms	69	2.22 (0.60–8.22)	0.231*	69	2.39 (0.51–11.24)	0.271
	Max. Adenosinef	70		0.574
SR
	Age	70	1.07 (1.01–1.13)	0.030*	68	1.10 (1.02–1.17)	0.010**
	Sex	70	3.72 (0.44–31.45)	0.228*	68	9.30 (0.60–144.53)	0.111
	Hypertension	70	0.40 (0.12–1.30)	0.127*	68	0.24 (0.06–0.98)	0.046**
	Dyslipidaemia	70	1.59 (0.46–5.48)	0.462
	Haem. Response	68	3.62 (0.79–16.46)	0.097*	68	13.06 (1.65–103.35)	0.015**
	Symptoms	68	0.00 (0.00)	0.999
	Max. Adenosine	68		0.352
All patients
	Age	140	1.03 (0.99–1.07)	0.146*	137	1.03 (0.99–1.08)	0.148
	Sex	140	4.35 (1.20–15.72)	0.025*	137	7.15 (1.65–31.08)	0.009**
	Hypertension	140	0.52 (0.26–1.06)	0.072*	137	0.36 (0.15–0.84)	0.018**
	Dyslipidaemia	140	2.14 (0.99–4.62)	0.054*	137	3.03 (1.19–7.72)	0.020**
	Haem. Response	137	2.92 (1.28–6.70)	0.012*	137	3.07 (1.14–8.32)	0.027**
	Symptoms	137	1.53 (0.55–4.30)	0.414
	Max. Adenosine AF	13,8140	0.30 (0.15–0.62)	0.537 0.001*	137	0.38 (0.17–0.85)	0.018**

**p < 0.05.

*p < 0.25.

^eHR increase over 10bpm.

^fMaximum rate of adenosine infusion (mcg/kg/min).