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. 2022 Dec 27;22:832. doi: 10.1186/s12888-022-04484-z

Table 3.

Comparison of empirical clusters based on TCI-NS and TCI-HA dimensions

Prototypic ↑↑HA / ↓NS Atypic ↑HA / NS t / χ2 / Fisher’s exact test1 pa d / ϕ
n = 338 (59%) n = 237 (41%)
n (%) / mean (SD) n (%) / mean (SD)
Sociodemographics
 sex (female) 202 (59.8%) 135 (57%) 0.41 .521 .03
 age 38.56 (12.58) 45.95 (14.70) 6.30 < .001 .55
 current partnership (yes) 151 (46.7%) 124 (56.1%) 4.60 .032* .09
 education (at least high school) 208 (61.5%) 157 (66.2%) 1.33 .249 .05
 children (yes) 86 (25.7%) 114 (48.5%) 31.63 < .001 .24
 smoking (yes) 67 (19.8%) 52 (21.9%) 0.55 .456 .03
SAD characteristics
 SPIN 43.85 (10.33) 38.01 (10.40) 6.65 < .001 .56
 SAD generalized 275 (86.2%) 190 (86.4%) 0.69 .707 .04
Former SAD treatment
 Psychotherapeutic / psychiatric 172 (50.9%) 108 (45.6%) 1.58 .209 .05
 medical 96 (68.6%) 42 (47.7%) 9.82 .002 .21
Family psychiatric history
 Any psychiatric disorder 105 (31.1%) 88 (37.1%) 2.30 .129 .06
 SAD 15 (4.4%) 16 (6.8%) 1.46 .227 .05
Comorbidities b
 Panic disorder 94 (28.1%) 61 (26.4%) 0.19 .665 .02
 Agoraphobia 125 (37.5%) 82 (35.2%) 0.33 .569 .02
 GAD 57 (17.0%) 29 (12.3%) 2.37 .123 .06
 Specific phobia 101 (30.1%) 77 (32.8%) 0.47 .492 .03
 Any anxiety disorder 209 (61.8%) 141 (59.5%) 0.86 .320 .02
 PTSD 5 (1.5%) 2 (0.8%) N/A1 .706 .03
 MDD 272 (80.5%) 172 (72.9%) 4.57 .032* .09
 APD 251 (74.5%) 137 (58.1%) 25.66 < .001 .21
 Alcohol-related disorder 74 (21.9%) 65 (27.4%) 2.33 .127 .06
 Substance-related 78 (23.1%) 68 (28.7%) 2.32 .128 .06
 Substance-related (cannabis) 1 (0.17%) 5 (0.87%) N/A1 .087 .09
BDI 22.77 (11.39) 17.02 (9.87) 6.29 < .001 .53
 BDI Item I 0.68 (0.68) 0.46 (0.66) 3.94 < .001 .33

n sample size, SD Standard deviation, t t-Test, χ2 chi-square, p p-Value, d Cohen’s d, ϕ Cramer’s V, SAD Social anxiety disorder, SPIN Social phobia inventory, GAD Generalized anxiety disorder, PTSD Posttraumatic stress disorder, MDD Major depression disorder, APD Avoidant personality disorder, BDI Beck depression inventory, BDI Item I = 0”I do not have any thoughts of harming myself; 3”I would kill myself if I could”, TCI Temperament and character inventory, HA Harm avoidance, NS Novelty seeking, N/A not available

n (%) refers to % within respective cluster

* nominally significant p < .05

a significant p-values after Benjamini–Hochberg adjustment are in bold

b results refer to observed lifetime comorbidities