Table 3.
Univariate and multivariate analysis of risk factors for 90-day PJP-related mortality
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95%CI) | P-value | |
| TMP-SMX > 7 days | 4.0 (1.4, 11.3) | 0.009 | 5.9 (1.1, 30.4) | 0.034 |
| Age, per 1 years old | 1.0 (1.0, 1.0) | 0.827 | ||
| Sex (female or male) | 1.2 (0.4, 3.8) | 0.757 | ||
| Interstitial Pneumonia (yes or no) | 1.9 (0.7, 5.5) | 0.210 | ||
| LDH > 500 U/L | 7.2 (1.6, 32.1) | 0.010 | 6.0 (1.1, 31.8) | 0.035 |
| Lymphopenia < 1000 cells/µL | 0.8 (0.2, 2.7) | 0.660 | ||
| CD4 + lymphocyte count < 200 cells/µL | 1.0 (0.3, 3.0) | 0.947 | ||
| Albumin < 30 g/L | 1.7 (0.5, 6.2) | 0.393 | ||
| Caspofungin (yes or no) | 3.7 (0.5, 28.0) | 0.210 | ||
| Methylprednisolone equivalent glucocorticoids (mg/d), per 10 mg/d | 1.9 (0.5, 6.7) | 0.353 | ||
PJP Pneumocystis jirovecii pneumonia, HR hazard ratio, CI confidence interval, TMP/SMX trimethoprim-sulfamethoxazole, LDH lactate dehydrogenase